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(Reuters) - A doctor exams mammograms, a special type of X-ray of the breasts, which is used to detect tumours as part of a regular cancer prevention medical check-up at a clinic in Nice, south eastern France January 4, 2008. REUTERS/Eric Gaillard
Integrin signalling adaptors: not only figurants in the cancer story
Nature Reviews Cancer 10, 858 (2010). doi:10.1038/nrc2967
Authors: Sara Cabodi, Maria del Pilar Camacho-Leal, Paola Di Stefano & Paola Defilippi
Current evidence highlights the ability of adaptor (or scaffold) proteins to create signalling platforms that drive cellular transformation upon integrin-dependent adhesion and growth factor receptor activation. The understanding of the biological effects that are regulated by these adaptors in tumours might be crucial for the...Read On
Contribution of positron emission tomography in pleural disease.
Rev Mal Respir. 2010 Oct;27(8):e47-53
Authors: Duysinx B, Corhay JL, Larock MP, Withofs N, Bury T, Hustinx R, Louis R
INTRODUCTION: Positron emission tomography (PET) now plays a clear role in oncology, especially in chest tumours. We discuss the value of metabolic imaging in characterising pleural pathology in the light of our own experience and review the literature. BACKGROUND: PET is particularly useful in characterising malignant pleural pathologies and is a factor of prognosis in mesothelioma. Metabolic imaging also provides clinical information for staging lung cancer, in researching the primary tumour in metastatic pleurisy and in monitoring chronic or recurrent pleural pathologies. CONCLUSIONS: PET should therefore be considered as a useful tool in the diagnosis of liquid or solid pleural pathologies.
PMID: 20965393 [PubMed - in process]www.ncbi.nlm.nih.gov
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