Oral Dis. 2005 Nov;11(6):338-49.
Number V Oral lichen planus: clinical features and management.
Dermatology Research Associates, Cincinnati, OH 45230, USA. firstname.lastname@example.org
Oral lichen planus (OLP) is a relatively common chronic inflammatory disorder affecting stratified squamous epithelia. Whereas in the majority of instances, cutaneous lesions of lichen planus (LP) are self-limiting and cause itching, oral lesions in OLP are chronic, rarely undergo spontaneous remission, are potentially premalignant and are often a source of morbidity. Current data suggest that OLP is a T cell-mediated autoimmune disease in which auto-cytotoxic CD8+ T cells trigger apoptosis of oral epithelial cells. The characteristic clinical aspects of OLP may be sufficient to make a correct diagnosis if there are classic skin lesions present. An oral biopsy with histopathologic study is recommended to confirm the clinical diagnosis and mainly to exclude dysplasia and malignancy. The most commonly employed and useful agents for the treatment of lichen planus (LP) are topical corticosteroids but other newer agents are available.
A case report of Metastasis of malignant mesothelioma to the oral gingiva.
Head Neck Oncol. 2011 Apr 22;3(1):21
Authors: Moser S, Beer M, Damerau G, Lubbers HT, Gratz KW, Kruse AL
ABSTRACT: INTRODUCTION: Metastatic mesothelioma to the oral cavity arises from the pleura or peritoneum and distant hematogenous metastases are seen in more than half of cases but only a few cases are reported to the oral cavity. Case A 75 year old male suffering from metastatic mesothelioma presents an hyperplasia of the attached gingiva. Malignant mesothelioma is a rare tumour arising from pleura, pericardium or peritoneum. CONCLUSION: This article highlights the importance of biopsy and histopathological diagnosis of oral lesions especially in case of a malignant history.
PMID: 21513537 [PubMed - as supplied by publisher]www.ncbi.nlm.nih.gov
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