Proteomics is critical for effective treatment of cancer, but still largely unknown. It seeks to identify small amounts of proteins or biomarkers in the blood serum of a patient, not only to diagnose the disease, but also to assess the evolution of the disease during therapy. This field of study is not as advanced as genomics and that although the genome of an organism is more or less constant, the proteome differs from one cell to another and from one moment to another. Experts say also that 80% of the proteins involved in cancer fall into the category of intrinsically disordered proteins (IDPs), unveiled a decade ago with the discovery of the genome, but whose function remains unknown.
Antiangiogenic therapy will also revolutionize future drugs. It is known that tumors need oxygen and nutrients from the organism to survive and grow. Anti-angiogenesis drugs “cut” this provision, so that the tumor eventually “die.” Several drugs have emerged such that not only benefit patients with cancer, but has also found its effectiveness to treat macular degeneration.
Stem cells are another important aspect in the fight against cancer. One of the characteristics of current treatments is that they target the cells ‘daughter’, reducing the tumor, while the long term can cause it to develop again, according to Gascón. The latest drugs attack the source, stem cell, and reduce the chances of relapse.
For all these advances be speeded up in time, it is essential that research results move as soon as possible to the daily life of patients. For this reason, it is fundamental the combination of basic and clinical research, ie, translational research, which seeks to transfer laboratory discoveries to patients as quickly as possible. www.christophermorganphotography.com
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